I wrote an article, “Will everyone be a responder to minoxidil?“, where it’s mentioned that there is actually a way for doctors to figure out if you are actually going to be a respondent or not of using minoxidil. Of course this is used for people suffering from androgenetic alopecia, but it can definitely be used for people hoping to use it for beard growth.

The main “culprit” I suppose you can call it is sulfotransferase enzymes. What is sulfotransferase enzymes? Well to be it quickly it is the enzyme the body uses to convert Minoxidil to it’s active counterpart Minoxidil sulfate.

Minoxidil non responder now responding with retinoids like tretinoin for beard growth.
Results may vary.

Well good thing for non-respondents to Minoxidil is there may be a way for you to be a respondent. Retinoids, whether a prescription of Tretinoin, or an OTC retinol serum could work just as well, albeit may be a bit slower than the former.

In this study, we demonstrate that topical tretinoin application influences the expression of follicular sulfotransferase. Of clinical significance, in our cohort, 43% of subjects initially predicted to be nonresponders to minoxidil were converted to responders following 5 days of topical tretinoin application.

Tretinoin enhances minoxidil response in androgenetic alopecia patients by upregulating follicular sulfotransferase enzymes.

So What Is Tretinoin?

Tretinoin is a derivative of vitamin A. It is used on the skin (topically) in the treatment of mild to moderate acne and on skin that has been damaged by excessive exposure to the sun.

If you aren’t able to get a prescription for tretinoin, then you can easily use OTC retinol. This is the one I used:

Tretinoin cream used to help non responders of minoxidil to become responders.

Where To Buy Tretinoin Online

Tretinoin can be obtained through a prescription when you are in the United States, but usually that is too much of a hassle and sometimes can be very expensive. Luckily, there’s a work around for this, Tretinoin can be purchase online through foreign pharmacies for a fraction of a price because you are buying generic not brand name.

One reputable website where I have purchased it and also so has the tretinoin subreddit found on reddit have successfully purchased it on AllDayChemist.com. Here’s the link that you can purchase it from…

Be aware, it will take 10 – 21 days to arrive, most of the time 12 or so days. Be careful and do not buy strong amounts, some people can see varying skin reactions if used too much. People build themselves up to daily applications. I recommend .05% Tretinoin, people report .1% is a bit too harsh.

How Much & When To Apply Tretinoin?

A pea sized amount will suffice and will be enough to cover your beard area that’s forsure. Apply it 30 minutes or an hour prior to applying Minoxidil to your face.

It’s recommended to apply every 2 or 3 days until your skin is accustomed to it after a few weeks.